New Listing - 06/22/2026


491 Iyannough Road, Barnstable, (Hyannis), MA, 02601

491 Iyannough Road, Barnstable, (Hyannis), MA, 02601

1960

3,215 sqft

Prime Commercial Location on Cape Cod with High-Visibility. Exceptional commercial opportunity. Currently the home of Nantucket Sound. This premier business location is known throughout the region for its unmatched exposure, excellent signage, and high traffic counts. Featuring 3,215 sq ft, a spacious main level, garage/warehouse, second floor office/storage and full basement. Positioned directly at the bustling Airport Rotary, abutting Staples Plaza, the property sits at the critical intersection of Route 28, Route 132 and Barnstable Road. These primary roadways serve as the main arteries connecting commuters and visitors to towns across the Cape, including Hyannis Harbor which is the hub to Nantucket and Martha's Vineyard. Located directly across the street from the Cape Cod Gateway Airport and just moments from vibrant Downtown Hyannis, this strategic location offers unparalleled regional accessibility. Capitalize on maximum drive-by visibility and a steady flow of potential customers in the commercial heart of the Cape. Perfect for retail, professional offices, or a flagship business hub.


Status:

Active

Town:

Barnstable

Type:

Commercial

Zoning:

HC

Cooling:

Central Air

Basement:

Full, Interior Entry

Levels:

1

Acreage:

0.36

Est. Taxes:

$8,234

Assessment

$828,600

Current Use

Retail

Permitted Use

Retail

Construction

Clapboard, Sheet Rock, Frame

Utilities

Cable Available, Electricity Available, Natural Gas Available

Lot Description:

Shopping, Medical Facility, Major Highway

School District:

Barnstable

Appliances:

Electric Water Heater

MLS #:

22603041


Community Info

School Info

Walk Score

Mass Transit

Yelp


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Listing courtesy of Nik J Atsalis, Premier Commercial 508-815-5700